New discovery could heal inherited heart diseases.
The multinational team of scientists working on this initiative hopes to begin clinical trials in five years.
Gene therapy could heal many hereditary illnesses. Genetic heart diseases may soon have a cure.
A team of scientists from the U.K., U.S., & Singapore is working on the CureHeart Project to find genetic medicines for cardiomyopathies, which make it harder for the heart to pump blood to the body.
The British Heart Foundation has awarded the researchers $37 million to fund this life-saving study.
Researchers will utilise base & prime editing to build & test the first cure for inherited heart muscle illnesses by shutting off defective genes.
While human studies haven't begun, animal trials have been successful.
"We've wanted to cure heart disease for decades. Most cardiac diseases are managed, not curable, says Richard Wright, M.D., a cardiologist in Santa Monica, CA.
At least for this odd array of illness situations where a certain gene is defective & we've identified it.
We could address the core problem in the cell & treat these patients. Those with hereditary cardiomyopathies have a 50/50 chance of passing on defective genes to their children.